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Keywords: glycoprotein
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Biochem Soc Trans (2017) 45 (1): 237–249.
Published: 15 February 2017
..., suggesting that stress-induced changes in O-GlcNAcylation are a conserved defense against injury that enable cellular remodeling to promote survival ( Table 1 ). Several studies have begun to delineate the mechanisms by which O -GlcNAc confers cytoprotection. chaperone glycoprotein heat shock...
Biochem Soc Trans (2011) 39 (1): 399–405.
Published: 19 January 2011
... candidate to identify new biomarkers. Backing this claim for a perspective in clinical practice are recent discoveries that even seemingly subtle changes in the glycan structure of glycoproteins, such as a N-glycan core substitution by a single sugar moiety, have far-reaching functional consequences...
Biochem Soc Trans (2010) 38 (6): 1453–1457.
Published: 24 November 2010
..., secondary to a primary defect of PPCA) belong to the glycoprotein storage diseases, whereas GM1-gangliosidosis (β-gal deficiency) is a glycosphingolipid storage disease. Identification of novel molecular pathways that are deregulated because of loss of enzyme activity and/or accumulation of specific...
Biochem Soc Trans (2008) 36 (6): 1453–1456.
Published: 19 November 2008
... glycoconjugate glycoprotein lectin mannan/mannose-binding lectin (MBL) Forty years ago, the number of examples where complex carbohydrates were implicated in cell recognition could literally have been counted on one hand. At that time also, lectins were identified with plant agglutinins...
Biochem Soc Trans (2008) 36 (6): 1472–1477.
Published: 19 November 2008
...Omai B. Garner; Linda G. Baum The formation of multivalent complexes of soluble galectins with glycoprotein receptors on the plasma membrane helps to organize glycoprotein assemblies on the surface of the cell. In some cell types, this formation of galectin–glycan lattices or scaffolds is critical...
Biochem Soc Trans (2008) 36 (6): 1491–1496.
Published: 19 November 2008
...@lectins.de 8 7 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 glycoprotein glycosylation inflammation lectin malignancy multivalency Figure 1 Key-like conformations of a bioactive ligand The pentasaccharide chain of the ganglioside G M1 (each sugar...