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Keywords: glutamine
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Biochem Soc Trans (2013) 41 (6): 1518–1524.
Published: 20 November 2013
... homoeostasis. GS (glutamine synthetase), which catalyses the ATP-dependent condensation of ammonia and glutamate to form glutamine, is an enzyme particularly found in astrocytes. GS plays a pivotal role in glutamate and glutamine homoeostasis, orchestrating astrocyte glutamate uptake/release and the glutamate...
Biochem Soc Trans (2010) 38 (5): 1220–1224.
Published: 24 September 2010
... hyperpolarized [5- 13 C]glutamine, and treatment-induced tumour cell necrosis can be imaged in vivo from measurements of the conversion of hyperpolarized [1,4- 13 C 2 ]fumarate into malate. Since these substrates are endogenous and, in some cases, have already been safely infused into patients, these techniques...