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Keywords: glial fibrillary acidic proteinClose
Biochem Soc Trans (2014) 42 (5): 1282–1285.
Published: 18 September 2014
... activation is the up-regulation of intermediate filaments, such as glial fibrillary acidic protein (GFAP) and vimentin. The role of astrocytosis in INCL was studied in a murine model lacking PPT1 and the intermediate filaments GFAP and vimentin (triple-knockout). This murine model of INCL with attenuated...
Biochem Soc Trans (2006) 34 (5): 738–742.
Published: 25 October 2006
... cells, as was shown in transgenic VP mouse lines having ectopic expression of VP [ 5 ]. AD Alzheimer's disease APP amyloid precursor protein CSF cerebrospinal fluid GFAP glial fibrillary acidic protein HSP heat-shock protein UBB ubiquitin B UFD ubiquitin...
Biochem Soc Trans (2006) 34 (1): 51–54.
Published: 20 January 2006
... increase in GFAP (glial fibrillary acidic protein) but additionally noted an accumulation of GFAP cleavage fragments in hippocampal homogenates. A time-dependent increase in hippocampal μ-calpain immunoreactivity within astrocytes suggests that its proteolytic activity may account for the cleavage of GFAP...