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Keywords: glial fibrillary acidic protein
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Articles

Astrocytosis in infantile neuronal ceroid lipofuscinosis: friend or foe?

Charles Shyng, Mark S. Sands
Journal: Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (5): 1282–1285.
https://doi.org/10.1042/BST20140188
Published: 18 September 2014
... activation is the up-regulation of intermediate filaments, such as glial fibrillary acidic protein (GFAP) and vimentin. The role of astrocytosis in INCL was studied in a murine model lacking PPT1 and the intermediate filaments GFAP and vimentin (triple-knockout). This murine model of INCL with attenuated...
View article titled, Astrocytosis in infantile neuronal ceroid lipofuscinosis: friend or foe?
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Articles

Molecular misreading: the occurrence of frameshift proteins in different diseases

F.W. van Leeuwen, J.M. Kros, W. Kamphorst, C. van Schravendijk, R.A.I. de Vos
Journal: Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 738–742.
https://doi.org/10.1042/BST0340738
Published: 25 October 2006
... cells, as was shown in transgenic VP mouse lines having ectopic expression of VP [ 5 ]. AD Alzheimer's disease APP amyloid precursor protein CSF cerebrospinal fluid GFAP glial fibrillary acidic protein HSP heat-shock protein UBB ubiquitin B UFD ubiquitin...
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Articles

Increased expression of glial fibrillary acidic protein fragments and μ-calpain activation within the hippocampus of prion-infected mice

B.C. Gray, P. Skipp, V.M. O'Connor, V.H. Perry
Journal: Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (1): 51–54.
https://doi.org/10.1042/BST0340051
Published: 20 January 2006
... increase in GFAP (glial fibrillary acidic protein) but additionally noted an accumulation of GFAP cleavage fragments in hippocampal homogenates. A time-dependent increase in hippocampal μ-calpain immunoreactivity within astrocytes suggests that its proteolytic activity may account for the cleavage of GFAP...
View article titled, Increased expression of <span class="search-highlight">glial</span> <span class="search-highlight">fibrillary</span> <span class="search-highlight">acidic</span> <span class="search-highlight">protein</span> fragments and μ-calpain activation within the hippocampus of prion-infected mice
Open the PDF for Increased expression of <span class="search-highlight">glial</span> <span class="search-highlight">fibrillary</span> <span class="search-highlight">acidic</span> <span class="search-highlight">protein</span> fragments and μ-calpain activation within the hippocampus of prion-infected mice in another window