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Keywords: genotoxin
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Biochem Soc Trans (2007) 35 (5): 1001–1004.
Published: 25 October 2007
...-apoptotic function of PKCδ in response to genotoxins. Our studies show that apoptotic signals induce rapid post-translational modification of PKCδ in the regulatory domain, which facilitates translocation of the kinase from the cytoplasm to the nucleus. Active caspase 3 also accumulates in the nucleus under...