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Keywords: genome-scale metabolic models
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Biochem Soc Trans (2021) 49 (4): 1663–1674.
Published: 20 July 2021
... into outputs. Now, genome sequencing and genome-scale metabolic models (GEMs) provide us with unprecedented detail about metabolic processes inside the cell. However, mostly due to computational complexity issues, the derived modelling approaches make surprisingly little use of thermodynamic concepts. Here, we...
Biochem Soc Trans (2020) 48 (5): 1889–1903.
Published: 17 September 2020
...Fernando Cruz; José P. Faria; Miguel Rocha; Isabel Rocha; Oscar Dias The current survey aims to describe the main methodologies for extending the reconstruction and analysis of genome-scale metabolic models and phenotype simulation with Flux Balance Analysis mathematical frameworks, via...
Includes: Supplementary data