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Keywords: genome integrity
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Articles
Biochem Soc Trans (2023) 51 (3): 1307–1317.
Published: 07 June 2023
... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . DNA repair genome integrity isogenic lines mutational signature whole genome sequencing Genetic changes affecting cell function and proliferation rate give rise...
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Biochem Soc Trans (2022) 50 (6): 1875–1884.
Published: 01 December 2022
... genome integrity prospermatogonia Z-DNA ZBTB43 Our recent study reveals a novel layer of global remodeling of the epigenome [ 1 ]. Chromatin composition includes covalent modifications of DNA and histone molecules. These marks can be faithfully maintained between cell divisions and provide...
Articles
Biochem Soc Trans (2022) 50 (4): 1105–1118.
Published: 30 August 2022
... 2022 The Author(s) 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cell cycle DNA damage response genome instability genome integrity mitosis...
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Biochem Soc Trans (2021) 49 (5): 2133–2141.
Published: 21 September 2021
... Cook ( jean_cook@med.unc.edu ) 2 7 2021 19 8 2021 31 8 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 cell cycle DNA replication and recombination genome integrity Animal development begins from a single...
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Biochem Soc Trans (2021) 49 (1): 93–105.
Published: 25 January 2021
... published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cancer chromatin genome integrity KDM4A The three-dimensional structure of chromatin is modulated by processes including nucleosome...
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Biochem Soc Trans (2020) 48 (5): 2317–2333.
Published: 21 October 2020
... 21 9 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 DNA damage response genome integrity lamins ovarian cancer Ovarian cancer is the major cause of deaths due to gynaecological malignancies which ranked third after...
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Biochem Soc Trans (2020) 48 (3): 823–836.
Published: 03 June 2020
...Sara Priego Moreno; Agnieszka Gambus DNA replication is a complex process that needs to be executed accurately before cell division in order to maintain genome integrity. DNA replication is divided into three main stages: initiation, elongation and termination. One of the key events during...
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Biochem Soc Trans (2017) 45 (5): 1173–1182.
Published: 22 September 2017
... structures from both directions [ 71 – 73 ]. Interestingly, in the absence of FANCJ, genomic deletions at G4 motifs were identified [ 69 ]. G4 genome integrity helicase in vivo G4 motifs are enriched at transcriptional start sites (TSSs) and promoter regions of genes thereby providing...