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Keywords: gene silencingClose
Biochem Soc Trans (2021) 49 (5): 1891–1903.
Published: 19 October 2021
... biology gene silencing nematode Ascaris programmed DNA elimination repeats and transposable elements In all species, including human and model organisms, gene expression requires comprehensive genome regulation that turns on and off genes, repeats, and other genetic elements. Indeed...
Biochem Soc Trans (2021) 49 (5): 2073–2079.
Published: 13 October 2021
.... Correspondence: Yang Yu ( email@example.com ) 29 3 2021 6 9 2021 15 9 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 epigenetics gene silencing piRNA transposons Genome integrity of eukaryotes is constantly...
In CollectionProtein structure and function
Biochem Soc Trans (2020) 48 (4): 1751–1763.
Published: 11 August 2020
...Alexandra D. Gurzau; Marnie E. Blewitt; Peter E. Czabotar; James M. Murphy; Richard W. Birkinshaw The structural maintenance of chromosomes hinge domain containing protein 1 (SMCHD1) is a large multidomain protein involved in epigenetic gene silencing. Variations in the SMCHD1 gene are associated...
Biochem Soc Trans (2013) 41 (4): 855–860.
Published: 18 July 2013
...Janina Pfaff; Gunter Meister Argonaute proteins interact with small RNAs and facilitate small RNA-guided gene-silencing processes. Small RNAs guide Argonaute proteins to distinct target sites on mRNAs where Argonaute proteins interact with members of the GW182 protein family (also known as GW...
Q.L. Zhou, J.G. Park, Z.Y. Jiang, J.J. Holik, P. Mitra, S. Semiz, A. Guilherme, A.M. Powelka, X. Tang, J. Virbasius, M.P. Czech
Biochem Soc Trans (2004) 32 (5): 817–821.
Published: 26 October 2004
...Q.L. Zhou; J.G. Park; Z.Y. Jiang; J.J. Holik; P. Mitra; S. Semiz; A. Guilherme; A.M. Powelka; X. Tang; J. Virbasius; M.P. Czech Using siRNA-mediated gene silencing in cultured adipocytes, we have dissected the insulin-signalling pathway leading to translocation of GLUT4 glucose transporters...
Biochem Soc Trans (2004) 32 (2): 355–359.
Published: 01 April 2004
... a novel approach which aims to elucidate the molecular changes that are induced after loss of tumour suppressor function. Using gene silencing tools, we mimic the loss of tumour suppressor function to identify key regulators of tumour initiation and progression. Loss of function of the tumour suppressor...
Biochem Soc Trans (2000) 28 (4): 386–390.
Published: 01 August 2000
... 2000 © 2000 Biochemical Society 2000 gene silencing histone deacetylation Sin3A CTCF, CCCTC-binding factor DBD, DNA-binding domain HDAC, histone deacetylase RXR, retinoid X receptor SMRT, silencing mediator for retinoic acid and thyroid hormone receptor T3, thyroid hormone T3R...