... while using the many genome copies as internal phosphate storage polymers. Very efficient gene conversion operates in haloarchaea and results in the unification of genome copies. Taken together, haloarchaea are excellent models to study many aspects of genome biology in prokaryotes, exhibiting...

.../desiccation resistance, gene redundancy and survival over geological times and at extraterrestrial sites. Experimental indications exist for all but one of these evolutionary advantages. Several of the advantages require gene conversion, which has been shown to be present and active in haloarchaea. 1...

... Muller's ratchet would be a mechanism leading to the equalization of genome copies, such as gene conversion. Using two species of methanogenic and halophilic archaea, it was shown that heterozygous cells containing different genomes simultaneously can be selected, exemplifying gene redundancy as one...

... can copy the lost information from the damaged chromosome's homologous pair. The haploid gametes that result carry a 3:1 ratio of alleles, rather than the expected 2:2. 1 email spencer@stats.ox.ac.uk 19 4 2006 © 2006 The Biochemical Society 2006 gene conversion HapMap...

... duplication fol- lowed by diversification through either point mutation or gene conversion. Deletions, inver- sions, transpositions and unequal cross are also likely to have played a role. All these types of mutation, on being coupled to selection, have allowed proteins with novel binding properties...

... units are turning out to be surprisingly polymorphic in structure and sequence. e-mail gloria.rudenko@ceid.ox.ac.uk 6 7 2000 © 2000 Biochemical Society 2000 antigenic variation gene conversion genome plasticity VSG, variant surface glycoprotein ESAG, expression-site...