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Keywords: fusion pore
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Articles
Biochem Soc Trans (2008) 36 (3): 294–299.
Published: 21 May 2008
... for two emerging concepts that affect insulin secretion at the level of individual granules: (i) the existence of specialized sites where granules dock in preparation for exocytosis; and (ii) post-exocytotic regulation of cargo release by the fusion pore. 1 To whom correspondence should...
Articles
Biochem Soc Trans (2003) 31 (4): 833–836.
Published: 01 August 2003
... a partially opened fusion pore. In an effort to quantify the population of insulin release that occurs by kiss-and-run, we used three fusion constructs, between: (1) synaptobrevin-2 [vesicle-associated membrane protein 2 (VAMP2)] and pHluorin, a pH-sensitive green fluorescent protein (GFP) (synapto ·pHluorin...
Articles
Biochem Soc Trans (2003) 31 (4): 837–841.
Published: 01 August 2003
... of typical mast cell granules. We have measured the time course of fusion pore expansion, and correlated it with release from the granule matrix. The fusion pore of mast cell granules grows in three stages. The initial expansion of the pore occurred at a rate of 5 nS/s, and in many cases an observable...