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Keywords: fumarate
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Biochem Soc Trans (2010) 38 (5): 1220–1224.
Published: 24 September 2010
... hyperpolarized [5- 13 C]glutamine, and treatment-induced tumour cell necrosis can be imaged in vivo from measurements of the conversion of hyperpolarized [1,4- 13 C 2 ]fumarate into malate. Since these substrates are endogenous and, in some cases, have already been safely infused into patients, these techniques...