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Keywords: fragmentation
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Biochem Soc Trans (2020) 48 (5): 1995–2002.
Published: 28 September 2020
... fragmentation spatially restricts beneficial repair signaling, enabling a localized response to focal injury. Conservation of mitochondrial fragmentation in response to cell and tissue damage across species demonstrates that this is a universal pro-survival adaptation to injury and suggests that mitochondrial...
Biochem Soc Trans (2010) 38 (4): 955–961.
Published: 26 July 2010
... an important role in both tau aggregation and neurodegeneration. On one hand, truncation of tau may generate amyloidogenic tau fragments that initiate the aggregation of tau, which in turn can cause toxicity. On the other hand, truncation of tau may result in tau fragments which induce neurodegeneration...