..., we review the role of PI3Ks in T-cell development and function. 1 To whom correspondence should be addressed (email klaus.okkenhaug@bbsrc.ac.uk ). 17 11 2006 © 2007 The Biochemical Society 2007 colitis forkhead box O (Foxo) p110δ phosphoinositide 3-kinase (PI3K) T-cell...

... highlights recent advances in our understanding of PI3K signalling pathways, in particular regulation of FoxO (forkhead box O) transcription factors, and their relevance to RA. fibroblast-like synoviocyte forkhead box O (FoxO) inflammation p53 up-regulated modulator of apoptosis (PUMA...

... (Manchester, U.K.) and G. Rutter (Imperial College London, U.K.). 1 email Jihye_Paik@dfci.harvard.edu 27 6 2006 © 2006 The Biochemical Society 2006 Akt angiogenesis forkhead box O (FOXO) homoeostasis phosphoinositide 3-kinase (PI3K) vascular cell type The FoxO family...

... resistance. cell fate forkhead box O (FOXO) phosphoinositide 3-kinase (PI3K) phosphorylation tumour 1 To whom correspondence should be addressed (email eric.lam@imperial.ac.uk ). 30 6 2006 © 2006 The Biochemical Society 2006 Figure 2 Activation of FOXO after stress...