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Keywords: force transmission
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Biochem Soc Trans (2011) 39 (6): 1729–1734.
Published: 21 November 2011
... at the nuclear envelope and suggest that many of the aforementioned defects can be attributed to disturbed force transmission between the nucleus and the cytoskeleton. Thus mutations in nesprins, SUN proteins or lamins, which have been linked to muscular dystrophies and cardiomyopathies, may weaken or completely...