.... The recent availability of overexpression and deletion strains for almost all of the transcription factor genes in the fission yeast Schizosaccharomyces pombe provides a valuable resource to better investigate transcription factors using systematic genetics. In the present paper, I review and discuss...

... by the Yamamoto laboratory as a suppressor of the uncontrolled meiosis driven by a pat1 mutant. Numerous studies from this laboratory and others have established the role of the Ste11 transcription factor as the master regulator of the switch between proliferation and differentiation in fission yeast...

... in fission yeast, but there are the INM proteins Lem2 and Man1, which contain the conserved LEM (Lap2/emerin/Man1) domain [ 19 ]. Moreover, these two proteins have overlapping functions together with another IMN protein named Ima1, and all three proteins contacts chromatin [ 19 – 21 ]. Figure 1...

...Jude Beaudoin; Seda Ekici; Fevzi Daldal; Samia Ait-Mohand; Brigitte Guérin; Simon Labbé The fission yeast Schizosaccharomyces pombe has been successfully used as a model to gain fundamental knowledge in understanding how eukaryotic cells acquire copper during vegetative growth. These studies have...

... functions as a platform for kinetochore formation, although the DNA sequence remains intact. Such epigenetic centromere inactivation occurs in cells of various eukaryotes harbouring ‘regional centromeres’, such as those of maize, fission yeast and humans, suggesting that the position of the active...

...Margarita Schlackow; Monika Gullerova Non-coding transcripts play an important role in gene expression regulation in all species, including budding and fission yeast. Such regulatory transcripts include intergenic ncRNA (non-coding RNA), 5′ and 3′ UTRs, introns and antisense transcripts...

.... A genetic model organism, the fission yeast Schizosaccharomyces pombe , has yielded robust models of cell-cycle control, applicable to higher eukaryotes. From a similar approach combining classical and chemical genetics, fundamental principles of transcriptional regulation by CDKs are now emerging...

... distribution. 1 To whom correspondence should be addressed (email fverde@med.miami.edu ). 7 10 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 Cdc42 cell polarity fission yeast morphogenesis symmetry breaking The ability to grow in a polarized...

... centromere chromosome heterochromatin fission yeast loss of heterozygosity (LOH) recombination Schizosaccharomyces pombe Swi6 Certain cancer cells, particularly solid tumours, are known for dramatic CIN (chromosome instability) phenotypes. Aneuploidy and other numerical disruptions (nCIN...

... is initiated by deadenylation, followed either by decapping and 5′→3′ degradation or by further 3′→5′ exonucleolysis. Our studies using RNA cRACE (circularization-based rapid amplification of cDNA ends) techniques indicate that mRNA decapping in the fission yeast Schizosaccharomyces pombe often does...

...Thomas D. Pollard We use fission yeast to study the molecular mechanism of cytokinesis. We benefit from a long history in genetic analysis of the cell cycle in fission yeast, which provided the most complete inventory of cytokinesis proteins. We used fluorescence microscopy of proteins tagged...

...Andrea Krapp; Viesturs Simanis The fission yeast septation initiation network, or SIN, is a signal transduction network that is required for septum formation in Schizosaccharomyces pombe . Its activity is tightly regulated through the cell cycle, to ensure proper co-ordination of mitosis...

...C.J. McInerny A fundamental process in biology is the mechanism by which cells duplicate and divide to produce two identical daughter cells. The fission yeast, Schizosaccharomyces pombe , has proved to be an excellent model organism to study the role that gene expression plays in this process...