...Katarzyna I. Wolanska; Mark R. Morgan The biophysical, mechanical and chemical characteristics of extracellular matrixes influence many cellular functions to control tissue homoeostasis and drive progression of cancer and inflammatory diseases. To maintain normal tissue function, fibronectin-rich...

...Iwona Kątnik-Prastowska; Magdalena Orczyk-Pawiłowicz The present paper describes concisely the expression and role of α(1,2)-linked fucose on some glycoconjugates as well as the detection, distribution and potential role of that glycotope on human soluble plasma and cellular fibronectins...

... in the exposition of terminal sialic acid and fucose isoforms in the amniotic fluid glycoconjugates, α 1 -acid glycoprotein and fibronectin during critical stages of pregnancy, i.e. second and third trimester, perinatal period, delivery and post-date pregnancy. The distinct amniotic glycoforms are suggested...

...Iain D. Campbell Recent studies of some proteins involved in the formation of focal adhesions are described. These include fibronectin, integrins, talin, Dok1 and filamin. Emphasis is placed on features that facilitate regulated assembly of complexes; these include a modular construction...

...J. Takagi Since the discovery of the RGD sequence motif as the essential cell attachment site in Fn (fibronectin), RGD-dependent ligand recognition by integrins has been the major focus of many integrin researches. Although many integrins recognize RGD-containing ligands, it is believed...

... of assessing how modular proteins are regulated and how they bind their various ligands. These aspects are illustrated here by recent studies of modular proteins carried out in our laboratory and elsewhere. Examples will include studies of ECM proteins, such as fibronectin, and proteins associated with focal...

...Mingcai Li © 2000 Biochemical Society 2000 fibronectin recombinant polypeptide metastasis 18th International Congress of Biochemistry and Molecular Biology: Abstracts from the 18th International Congress of Biochemistry and Molecular Biology, 16–20 July 2000, Birmingham, UK...

... and sufficient for cytotrophoblast column development. Proliferation of trophoblast occurs, followed by differentiation into a columnar cell phenotype in which cells remain attached to one another and to the ECM. At this stage, interaction between fibronectin and integrin α5β1 at the cell surface stabilizes...