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Keywords: ferritin
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Biochem Soc Trans (2013) 41 (6): 1588–1592.
Published: 20 November 2013
...Michaela C. Hohnholt; Ralf Dringen Astrocytes are considered key regulators of the iron metabolism of the brain. These cells are able to rapidly accumulate iron ions and various iron-containing compounds, store iron efficiently in ferritin and also export iron. The present short review summarizes...
Biochem Soc Trans (2010) 38 (2): 536–538.
Published: 22 March 2010
... in vivo increases the risk of onset of neurodegenerative diseases and nanoparticles are apparently able to kill neurons in vitro . We suggested that presynaptic terminals of neurons are another target for nanoparticles, beyond the already established microglial cells. Ferritin was chosen as a prototypic...
Biochem Soc Trans (2008) 36 (6): 1313–1316.
Published: 19 November 2008
...Anuja Mehta; Abhyuday Deshpande; Fanis Missirlis Ferritin, a symmetrical 24-subunit heteropolymer composed of heavy and light chains, is the primary iron-storage molecule in bacteria, plants and animals. We used a genetically engineered strain of the model organism Drosophila melanogaster which...
Biochem Soc Trans (2008) 36 (6): 1282–1287.
Published: 19 November 2008
... is cleaved in a non-amyloidogenic pathway within its Aβ domain to release the neuroprotective APP ectodomain, APP(s). To adapt and counteract metal-catalysed oxidative stress, as during reperfusion from stroke, iron and cytokines induce the translation of both APP and ferritin (an iron storage protein...