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Keywords: feedback loop
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Biochem Soc Trans (2010) 38 (5): 1281–1285.
Published: 24 September 2010
... in the pathway itself, opening the possibility for positive and negative autoregulation (see Figure 2 ). The feedback loop via axin-2 was included in several modelling approaches [ 12 , 13 , 21 ]. Its effect with respect to the β-catenin steady state was studied in various mutants [ 12 ]. The increase in the β...