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Keywords: feedback
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Biochem Soc Trans (2021) 49 (4): 1515–1527.
Published: 10 August 2021
..., polarity and secretion of a range of biologically active components. Recent studies highlight that spatio-temporal regulation of Hippo pathway components are central to precisely controlling its context-dependent dynamic activity. Several levels of feedback are integrated into the Hippo pathway, which...
Biochem Soc Trans (2014) 42 (4): 770–775.
Published: 11 August 2014
... entered clinical trials. However, resistance to these inhibitors, either intrinsic to the tumour or acquired during treatment, remains a major problem in targeted therapeutics. One of the mechanisms by which tumours become resistant is the rewiring of the signalling networks via feedback, by which...
Biochem Soc Trans (2013) 41 (4): 939–943.
Published: 18 July 2013
... of the cell and appropriately dictates whether the cell will actively favour energy- and amino-acid-consuming anabolic processes such as cellular growth, or energy- and amino-acid-generating catabolic processes such as autophagy. The present review discusses important feedback mechanisms between these three...
Biochem Soc Trans (2010) 38 (5): 1242–1246.
Published: 24 September 2010
... cell cycles are always driven by a negative-feedback loop amplified by double-negative feedbacks (antagonism). 1 To whom correspondence should be addressed (email bela.novak@bioch.ox.ac.uk ). 8 3 2010 The high Cdk activity state is stabilized by the mitotic checkpoint...
Biochem Soc Trans (2005) 33 (3): 507–515.
Published: 01 June 2005
...O. Wolkenhauer; S.N. Sreenath; P. Wellstead; M. Ullah; K.-H. Cho A mathematical understanding of regulation, and, in particular, the role of feedback, has been central to the advance of the physical sciences and technology. In this article, the framework provided by systems biology is used to argue...
Biochem Soc Trans (2003) 31 (3): 719–722.
Published: 01 June 2003
... and differentiation. enzyme feedback kinetics non-linearity oscillation Abbreviations used: PFK, phosphofructokinase; BZ reaction, Belousov–Zhabotinskii reaction; PO, peroxidase-oxidase. 1 e-mail amcdonld@tcd.ie The Behaviour of Enzymes in Cells, a Biochemical Society-supported meeting...
Biochem Soc Trans (2002) 30 (2): 227–231.
Published: 01 April 2002
... glycogenolytic flux to be measured from Key words: ATP, feedback flux, oxidative phosphorylation, stoichiometry. Abbreviations used: CK, creatine kinase; PCr, phosphocreatine; Po,, partial pressure of oxygen. 'To whom correspondence should be addressed: I959 Pacific Ave. NE, Box 357 I 15, University...