1-24 of 24
Keywords: fatty acid
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem Soc Trans (2010) 38 (4): 934–939.
Published: 26 July 2010
...Max J. Cryle The cytochromes P450 (P450s) are a superfamily of oxidative haemoproteins that are capable of catalysing a vast range of oxidative transformations, including the oxidation of unactivated alkanes, often with high stereo- and regio-selectivity. Fatty acid hydroxylation by P450s...
Articles
Biochem Soc Trans (2008) 36 (6): 1317–1321.
Published: 19 November 2008
... and putative structure of the major zinc site on albumin been reported. Intriguingly, this site is located at the interface between two domains, and involves two residues from each of domains I and II. Comparisons of X-ray crystal structures of free and fatty-acid bound human serum albumin suggest that zinc...
Articles
Biochem Soc Trans (2008) 36 (5): 950–954.
Published: 19 September 2008
...Ruth Brownlie; Rachel M. Mayers; Jackie A. Pierce; Anna E. Marley; David M. Smith GPR40 (G-protein-coupled receptor 40) has been shown to be a physiologically relevant receptor for long-chain fatty acids. It is a family A G-protein-coupled receptor highly expressed in the β-cell where it increases...
Articles
Biochem Soc Trans (2008) 36 (5): 885–890.
Published: 19 September 2008
... be addressed (email hindrik.mulder@med.lu.se ). 26 6 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 coupling signal fatty acid islet lipolysis orlistat triacylglycerol The metabolic perturbations in Type 2 diabetes are not restricted to the metabolism...
Articles
Biochem Soc Trans (2008) 36 (3): 360–362.
Published: 21 May 2008
...Gabriela Ridner; Reut Bartoov-Shifman; Tatyana Zalogin; Tali Avnit-Sagi; Keren Bahar; Revital Sharivkin; Lia Kantorovich; Sara Weiss; Michael D. Walker GPR40 {FFAR1 [non-esterified (‘free’) fatty acid receptor 1]} is a G-protein-coupled receptor expressed preferentially in pancreatic β-cells. GPR40...
Articles
Biochem Soc Trans (2007) 35 (5): 1199–1202.
Published: 25 October 2007
... with issues specific to fatty acid sensing and not the emergent acid pH-sensing mechanisms that may also be activated in the presence of free fatty acids. 1 email john.mclaughlin@manchester.ac.uk 18 6 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007...
Articles
Biochem Soc Trans (2007) 35 (3): 470–471.
Published: 22 May 2007
... receptors and foam cell formation, or even improve the atherogenic risk of these particles. 1 To whom correspondence should be addressed (email rcabello@ig.csic.es ). 15 12 2006 © 2007 Biochemical Society 2007 chylomicron fatty acid foam cell scavenger receptor triacylglycerol...
Articles
Biochem Soc Trans (2006) 34 (5): 802–805.
Published: 25 October 2006
... fatty acid metabolism by altering NAD/NADH or by facilitating cycling of fatty acid anions. Recently, UCP2 has been proposed to keep insulin secretion low during starvation, a function under the control of the transcription co-repressor, surtuin-1, which has been shown to bind to the UCP2 promoter...
Articles
Biochem Soc Trans (2006) 34 (5): 770–773.
Published: 25 October 2006
...D.K. Covington; C.A. Briscoe; A.J. Brown; C.K. Jayawickreme Recent deorphanization efforts have paired the G-protein-coupled receptors GPR40, GPR41 and GPR43 with fatty acids as endogenous ligands. While carboxylic acids have been historically known to serve as fuel sources and biomarkers...
Articles
Biochem Soc Trans (2006) 34 (5): 819–823.
Published: 25 October 2006
... of the 3243A>G mutation are generally not obese. The mutation also results in enhanced radical production by mitochondria. We propose that this mutation leads to the development of diabetes due to an inappropriate storage of triacylglycerols within adipocytes. The result is a fatty acid-induced...
Articles
Biochem Soc Trans (2006) 34 (6): 1370–1375.
Published: 25 October 2006
...S. Klumpp; M.-C. Thissen; J. Krieglstein This mini-review highlights the involvement of PP2C (protein phosphatase type 2C) family members α and β in apoptosis. The activity of these isoenzymes can be stimulated by unsaturated fatty acids with special structural features, e.g. oleic acid. Those...
Articles
Biochem Soc Trans (2005) 33 (5): 1045–1048.
Published: 26 October 2005
...F. Karpe; G.D. Tan Insulin resistance is often seen as a consequence of obesity and there are several possible links between adipose tissue function and insulin resistance determined in other organs such as skeletal muscle or liver. One such link is the regulation of NEFA (non-esterified fatty acid...
Articles
Biochem Soc Trans (2005) 33 (5): 1182–1185.
Published: 26 October 2005
...J. Garbarino; S.L. Sturley Fatty acids and sterols are vital components of all eukaryotic cells. Both are used as building blocks for numerous cellular processes such as membrane biosynthesis or hormone production (sterols). Furthermore, these compounds elicit a variety of effects intracellularly...
Articles
Biochem Soc Trans (2005) 33 (1): 311–315.
Published: 01 February 2005
...V.A. Drover; N.A. Abumrad CD36 is an important regulator of lipid metabolism in vivo due to its role in the facilitated uptake of long-chain FAs (fatty acids). CD36-deficient mice display reduced TAG (triacylglycerol) in muscle, but elevated hepatic TAG. Also, insulin sensitivity is enhanced...
Articles
Biochem Soc Trans (2004) 32 (6): 999–1002.
Published: 26 October 2004
...H.M. Roche Nutrition is a key environmental factor that is particularly involved in the pathogenesis and progression of several polygenic, diet-related diseases. Nutrigenomics refers to the interaction between nutrition and the human genome. Dietary fatty acids interact with multiple nutrient...
Articles
Biochem Soc Trans (2004) 32 (1): 55–58.
Published: 01 February 2004
... of dietary fatty acids on the synthesis, secretion and metabolism of chylomicrons, the large triacylglycerol-rich lipoproteins synthesized in the enterocyte following the digestion and absorption of dietary fat. This brief review considers current approaches to the investigation of chylomicron synthesis...
Articles
Biochem Soc Trans (2004) 32 (1): 59–64.
Published: 01 February 2004
... of a process by which the liver protects vulnerable body tissues from excess lipotoxic non-esterified (‘free’) fatty acids in the plasma. 1 To whom correspondence should be addressed (e-mail geoff.gibbons@mrl.ox.ac.uk ). 44th International Conference on the Bioscience of Lipids, a meeting held...
Articles
Biochem Soc Trans (2003) 31 (6): 1130–1132.
Published: 01 December 2003
...P.A. Grimaldi PPAR δ (peroxisome proliferator-activated receptor δ)-specific agonists decrease plasma lipids and insulinaemia in obese animals. As skeletal muscle is one of the major organs for fatty acid catabolism, we have investigated the roles of the nuclear receptor in the control of muscle...
Articles
Biochem Soc Trans (2003) 31 (6): 1143–1151.
Published: 01 December 2003
...M.J. Holness; M.C. Sugden PDC (pyruvate dehydrogenase complex) catalyses the oxidative decarboxylation of pyruvate, linking glycolysis to the tricarboxylic acid cycle. Regulation of PDC determines and reflects substrate preference and is critical to the ‘glucose–fatty acid cycle’, a concept...
Articles
Biochem Soc Trans (2003) 31 (1): 162–168.
Published: 01 February 2003
..., a Biochemical Society-sponsored meeting held at University of Dundee, Scotland, 12–14 September 2002 10 September 2002 Copyright 2003 Biochemical Society 2003 AMP-activated protein kinase metabolism cholesterol exercise fatty acid glucose Abbreviations used: AMPK, AMP...
Articles
Biochem Soc Trans (2000) 28 (6): 729–732.
Published: 01 December 2000
... of the phospholipids phosphatidylglycerol (PG), phosphatidylcholine (PC) and phosphatidyl- ethanolamine in both photosynthetic bacteria [2,3] Key words: dgdl mutant, fatty acid, lipid-substitution hypothesis, phospholipid. Abbreviations used: DGDG, digalactosyldiacylglycerol ; PG, phos- phatidylglycerol; PC...
Articles
Biochem Soc Trans (2000) 28 (6): 575–577.
Published: 01 December 2000
... that reliable estimates of acyl-CoA ester concentrations have been made for plants. 1 To whom correspondence should be addressed (e-mail trll@cnap.york.ac.uk ) 2 E-mail iag1@cnap.york.ac.uk 26 6 2000 © 2000 Biochemical Society 2000 fatty acid HPLC lipid Lipid Analysis n...
Articles
Biochem Soc Trans (2000) 28 (6): 907–910.
Published: 01 December 2000
...F. Jemal; M. Zarrouk; M. H. Ghorbal Seedlings (2 weeks old) of pepper ( Capsicum annum ) were grown in nutrient solution with added CdCl 2 (10 or 50μM) for 7 days. In Cd-treated plants, changes in acyl lipids and fatty acid composition were investigated. Cd particularly lowered the amount...
Articles
Biochem Soc Trans (2000) 28 (6): 950–953.
Published: 01 December 2000
... to simultaneously convert 13-OTA to the corresponding ω-dicarboxylic acid and ω-hydroxy carboxylic acid derivatives. 1 To whom correspondence should be addressed (e-mail anunez@arserrc.gov ) 23 6 2000 © 2000 Biochemical Society 2000 cleavage dicarboxylic acid fatty acid hydroperoxide...