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Keywords: extracellular vesicles
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Biochem Soc Trans (2022) 50 (6): 1773–1783.
Published: 09 December 2022
... 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 extracellular vesicles lysosome mitochondria-free mitochondrial quality control parkinsonism The quality control of mitochondria is essential for the homeostasis and function...
Biochem Soc Trans (2022) 50 (5): 1303–1314.
Published: 16 September 2022
..., or preformed fibrils, have been implicated as the causative agent in the degeneration of neuronal processes, including the dysfunction of axonal transport, mitochondrial activity, and ultimately cellular death. Extracellular vesicles (EVs) have been strongly implicated in the propagation of PD pathology...
Biochem Soc Trans (2021) 49 (1): 313–325.
Published: 01 February 2021
... later shown to result from the common mechanism of mitochondrial superoxide overproduction. More recently, non-coding RNA, extracellular vesicles, and sodium-glucose cotransporter-2 inhibitors were shown to affect glucose-induced endothelial dysfunction. Endothelial cells also metabolize glucose...
Biochem Soc Trans (2020) 48 (5): 2335–2345.
Published: 14 October 2020
...Samuel Lewin; Stuart Hunt; Daniel W. Lambert Extracellular vesicles (EV) are implicated in a variety of functions affecting the extracellular matrix (ECM), including matrix degradation, cross-linking of matrix proteins and matrix calcification. These processes are important in many physiological...
Biochem Soc Trans (2020) 48 (5): 2079–2088.
Published: 01 September 2020
...Thanh Kha Phan; Dilara Ceyda Ozkocak; Ivan Ka Ho Poon Extracellular vesicles (EVs), membrane-bound vesicles that are naturally released by cells, have emerged as new therapeutic opportunities. EVs, particularly exosomes and microvesicles, can transfer effector molecules and elicit potent responses...
Biochem Soc Trans (2019) 47 (4): 1005–1012.
Published: 18 July 2019
...Carolina Coelho; Arturo Casadevall It is now over 30 years since the discovery of extracellular vesicles (EVs) in Gram-negative bacteria. However, for cell-walled microbes such as fungi, mycobacteria and Gram-positive bacteria it was thought that EV release would be impossible, since...
Biochem Soc Trans (2019) 47 (2): 509–516.
Published: 05 April 2019
...Lois R. Grant; Ivana Milic; Andrew Devitt Apoptosis is an essential process for normal physiology and plays a key role in the resolution of inflammation. Clearance of apoptotic cells (ACs) involves complex signalling between phagocytic cells, ACs, and the extracellular vesicles (EVs) they produce...
Biochem Soc Trans (2018) 46 (5): 1137–1146.
Published: 09 October 2018
... the cancer community and the pharmaceutical industry in recent years involves the ability of cancer cells to generate multiple distinct types of non-classical secretory vesicles, generally referred to as extracellular vesicles (EVs). Microvesicles (MVs) represent one of the major classes of EVs...
Biochem Soc Trans (2018) 46 (5): 1129–1136.
Published: 21 September 2018
... deaths. The levels of pro-inflammatory and pro-cachectic factors were significantly up-regulated in cachexia patients when compared with the patients who were without cachexia. It is becoming evident that these factors work synergistically to induce cancer cachexia. Extracellular vesicles (EVs) including...