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Keywords: extracellular pHClose
Journal: Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 899–902.
Published: 25 October 2006
..., they differ more widely in the way their opening and closing, the gating, is governed. TASK and TALK subfamily proteins are two-pore region KCNK K + channels gated open by extracellular pH. We discuss the mechanism for this gating in terms of electrostatic effects on the pore changing the occupancy and open...