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Keywords: exchange protein directly activated by cAMP (Epac)
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (2): 257–264.
Published: 20 March 2014
.... Dekker F.J. Maarsingh H. Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions Pharmacol. Rev. 2013 65 670 709 11 Niimura M. Miki T. Shibasaki T. Fujimoto W. Iwanaga T. Seino S...
Articles
Stephen Boulton, Madoka Akimoto, Bryan VanSchouwen, Kody Moleschi, Rajeevan Selvaratnam, Rajanish Giri, Giuseppe Melacini
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (2): 302–307.
Published: 20 March 2014
... for the treatment of cardiovascular diseases. 1 To whom correspondence should be addressed (email melacin@mcmaster.ca ). 17 12 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 cAMP exchange protein directly activated by cAMP (Epac) hyperpolarization-activated...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 89–97.
Published: 23 January 2014
... the blood and the surrounding tissue. The vasculature expresses three cAMP effector proteins: PKA (protein kinase A), CNG (cyclic-nucleotide-gated) ion channels, and the most recently discovered Epacs (exchange proteins directly activated by cAMP). Epacs are a family of GEFs (guanine-nucleotide-exchange...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 215–218.
Published: 19 January 2012
... therapeutic efficacy of cAMP-elevating drugs while minimizing the adverse effects usually associated with these agents. cytokine exchange protein directly activated by cAMP (Epac) Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 219–223.
Published: 19 January 2012
.... © The Authors Journal compilation © 2012 Biochemical Society 2012 allostery cAMP cGMP chemical shift covariance analysis (CHESCA) exchange protein directly activated by cAMP (Epac) nuclear magnetic resonance (NMR) protein dynamics cAMP is an ancient second messenger that controls...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 51–57.
Published: 19 January 2012
..., phosphoinositide 3-kinase); PLD, phospholipase D; STEF, Sif- and Tiam1-like exchange factor. cAMP exchange protein directly activated by cAMP (Epac) G-protein-coupled receptor guanine-nucleotide-exchange factor heart failure protein kinase A (PKA) cAMP is a universal second messenger which...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (4): 468–471.
Published: 21 July 2006
... dmfc2@cam.ac.uk ). 13 3 2006 © 2006 The Biochemical Society 2006 adenylate cyclase (AC) calcium cAMP cyclic nucleotide-gated channel (CNGC) exchange protein directly activated by cAMP (Epac) fluorescence resonance energy transfer (FRET) phosphodiesterase (PDE) Numerous...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (6): 1327–1329.
Published: 26 October 2005
... of future therapeutics for diseases where cAMP signalling through Rap1 is improperly regulated. 1 email S.Yarwood@bio.gla.ac.uk 13 6 2005 © 2005 The Biochemical Society 2005 cAMP exchange protein directly activated by cAMP (EPAC) light chain 2 microtubule-associated protein...
Articles
I. McPhee, L.C.D. Gibson, J. Kewney, C. Darroch, P.A. Stevens, D. Spinks, A. Cooreman, S.J. MacKenzie
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (6): 1330–1332.
Published: 26 October 2005
.... Wittinghofer A. Bos J.L. J. Biol. Chem. 2003 278 38548 38556 1 To whom correspondence should be addressed (email ian.mcphee@scottish-biomedical.com ). 4 7 2005 © 2005 The Biochemical Society 2005 Alzheimer's disease cAMP exchange protein directly activated...
Articles
J.L. Bos, K. de Bruyn, J. Enserink, B. Kuiperij, S. Rangarajan, H. Rehmann, J. Riedl, J. de Rooij, F. van Mansfeld, F. Zwartkruis
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (1): 83–86.
Published: 01 February 2003
... meeting held at University of Liverpool, Liverpool, 4–6 September 2002 6 September 2002 Copyright 2003 Biochemical Society 2003 cAMP exchange protein directly activated by cAMP (Epac) integrin Abbreviations used: AF6; ALL1-fused gene from chromosome 6; Epac, exchange...
