1-10 of 10
Keywords: exchange protein directly activated by cAMP (EPAC)
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem Soc Trans (2014) 42 (2): 302–307.
Published: 20 March 2014
..., irrespective of whether it is apo or holo. 1 To whom correspondence should be addressed (email melacin@mcmaster.ca ). 17 12 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 cAMP exchange protein directly activated by cAMP (Epac) hyperpolarization...
Articles
Biochem Soc Trans (2014) 42 (2): 257–264.
Published: 20 March 2014
... for the treatment of cardiac disorders. 1 To whom correspondence should be addressed (email Frank.Lezoualch@inserm.fr ). 20 1 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 cAMP cardiac disease exchange protein directly activated by cAMP (Epac) G-protein...
Articles
Biochem Soc Trans (2014) 42 (1): 89–97.
Published: 23 January 2014
... the blood and the surrounding tissue. The vasculature expresses three cAMP effector proteins: PKA (protein kinase A), CNG (cyclic-nucleotide-gated) ion channels, and the most recently discovered Epacs (exchange proteins directly activated by cAMP). Epacs are a family of GEFs (guanine-nucleotide-exchange...
Articles
Biochem Soc Trans (2012) 40 (1): 51–57.
Published: 19 January 2012
... 2012 Biochemical Society 2012 cAMP exchange protein directly activated by cAMP (Epac) G-protein-coupled receptor guanine-nucleotide-exchange factor heart failure protein kinase A (PKA) cAMP is a universal second messenger which is produced from ATP by adenylate cyclase upon...
Articles
Biochem Soc Trans (2012) 40 (1): 215–218.
Published: 19 January 2012
... and recruiting transcriptional co-activators [ 1 , 2 ]. cytokine exchange protein directly activated by cAMP (Epac) Janus kinase (JAK) signal transducer and activator of transcription (STAT) suppressor of cytokine signalling (SOCS) ubiquitin ligase ...
Articles
Biochem Soc Trans (2012) 40 (1): 219–223.
Published: 19 January 2012
... compilation © 2012 Biochemical Society 2012 allostery cAMP cGMP chemical shift covariance analysis (CHESCA) exchange protein directly activated by cAMP (Epac) nuclear magnetic resonance (NMR) protein dynamics cAMP is an ancient second messenger that controls a multitude of essential...
Articles
Biochem Soc Trans (2006) 34 (4): 468–471.
Published: 21 July 2006
... interaction with other signalling pathways. adenylate cyclase (AC) calcium cAMP cyclic nucleotide-gated channel (CNGC) exchange protein directly activated by cAMP (Epac) fluorescence resonance energy transfer (FRET) phosphodiesterase (PDE) Numerous hormones and neurotransmitters, acting...
Articles
Biochem Soc Trans (2005) 33 (6): 1330–1332.
Published: 26 October 2005
... disease cAMP exchange protein directly activated by cAMP (EPAC) guanine nucleotide-exchange factor (GEF) protein kinase A (PKA) Rap Although the effects of cAMP-mediated signalling are wide ranging, there are only two general cAMP effectors, i.e. proteins that are activated by binding to cAMP...
Articles
Biochem Soc Trans (2005) 33 (6): 1327–1329.
Published: 26 October 2005
... of future therapeutics for diseases where cAMP signalling through Rap1 is improperly regulated. cAMP exchange protein directly activated by cAMP (EPAC) light chain 2 microtubule-associated protein (MAP) protein kinase A (PKA) Rap1 Many extracellular physiological signalling agents increase...
Articles
Biochem Soc Trans (2003) 31 (1): 83–86.
Published: 01 February 2003
... of Key words: cAMP, exchange protein directly activated by cAMP (Epac), integrin. Abbreviations used: AF6; ALL1-fused gene from chromosome 6; Epac, exchange protein directly activated by cAMP; ERK, extracellular-signal-regulated kinase; GAP, GTPase-activating protein; GEF, guanine nucleotide exchange...