... clock has undergone considerable development over the years, and it retains profound relevance in the genomic era. In this mini-review, we describe the history of the molecular clock, its impact on evolutionary theory, the challenges brought by evidence of evolutionary rate variation among species...

... 2009 coding potential de novo gene formation evolutionary rate gene duplication orphan gene transposable element In all genome sequence projects undertaken to date, researchers have identified a surprisingly large number of genes that show no similarity to genes from other species...