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Keywords: enzyme activity
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Biochem Soc Trans (2022) 50 (1): 473–485.
Published: 07 February 2022
... ligase NEDD4 enzyme activity metabolism ubiquitin signaling By targeting at least one third of our proteome, ubiquitin (Ub) affects virtually all biological pathways including those regulating cell growth and death, development, differentiation, inflammation, protein trafficking...
Biochem Soc Trans (2020) 48 (4): 1737–1750.
Published: 17 July 2020
... and the Biochemical Society under a transformative agreement with CAUL. enzyme activity post-translational modification RBR ubiquitin ligases ubiquitin ligases ubiquitin signalling The post-translational modification of proteins by addition of a single ubiquitin molecule (monoubiquitination...
Biochem Soc Trans (2017) 45 (1): 163–172.
Published: 15 February 2017
... this mechanism also holds true for LRRK2 awaits further confirmation. The function of the GTPase domain and its contribution to the pathogenic actions of familial LRRK2 mutations in PD models remains incompletely characterized. cell death enzyme activity leucine-rich repeat kinase neurodegeneration...
Biochem Soc Trans (2007) 35 (6): 1543–1546.
Published: 23 November 2007
... on enzyme activity in terms of a rapidly reversible active–inactive (but not denatured) transition, revealing an additional and reversible mechanism for enzyme activity loss in addition to irreversible thermal inactivation at high temperatures. Two new thermal parameters, T eq and Δ H eq , describe...