... it. 1 email d.g.hardie@dundee.ac.uk 11 9 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 AMP-activated protein kinase (AMPK) cancer cell metabolism energy balance mitochondrion Type 2 diabetes Living cells are molecular machines that require...

... to obesity in both childhood and adulthood; however, the mechanisms underlying this link are poorly understood. A variety of animal models have been established to try and uncover the developmental programming effects of maternal early life nutrition on energy balance regulation and the mechanisms behind...

... factor linking the clinical manifestations of the metabolic syndrome. 1 To whom correspondence should be addressed (email ajv22@medschl.cam.ac.uk ). 20 6 2005 © 2005 The Biochemical Society 2005 energy balance homoeostasis insulin resistance lipid metabolism mouse...