... 29 10 2020 11 11 2020 © 2020 The Author(s) 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . endosomal sorting endosome microfilaments...

...Han Han; Christopher P. Hill The progression of ESCRT (Endosomal Sorting Complexes Required for Transport) pathways, which mediate numerous cellular membrane fission events, is driven by the enzyme Vps4. Understanding of Vps4 mechanism is, therefore, of fundamental importance in its own right...

... face of the endosome and generates vesicles that bud into the endosome lumen, but somehow escapes encapsulation itself. This machinery is termed the ESCRT (endosomal sorting complexes required for transport) pathway, a series of multi-protein complexes and accessory factors first identified in yeast...

... by Portland Press Limited on behalf of the Biochemical Society 2017 cell adhesion cell migration endosomal sorting protein kinase B Rab5 trafficking APPL1 integrates signaling cross-talk via multiple domains that mediate protein and lipid interactions [ 3 , 4 ]. The N-terminal BAR (Bin...

... unique vacuole type per cell. endosomal sorting lysosomes receptors trafficking vacuole © 2016 The Author(s) 2016 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0...

... are increasingly being linked with human disease. 23 10 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 endosomal sorting post-synaptic density 95/discs large/zonula occludens (PDZ) domain protein 4.1/ezrin/radixin/moesin (FERM)-like domain retromer sorting nexins...

... Journal compilation © 2011 Biochemical Society 2011 early endosome endosomal sorting motor protein Rab protein sorting nexin (SNX) Eukaryotic cells are compartmentalized into distinct organelles that are composed of specific cohorts of proteins and lipids. Precise transport mechanisms...

...Jeremy Carlton The ESCRT (endosomal sorting complex required for transport) machinery is a group of multisubunit protein complexes conserved across phyla that are involved in a range of diverse cellular processes. ESCRT proteins regulate the biogenesis of MVBs (multivesicular bodies...