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Keywords: endosomal sorting
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Articles
Biochem Soc Trans (2020) 48 (6): 2377–2386.
Published: 10 December 2020
... 29 10 2020 11 11 2020 © 2020 The Author(s) 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . endosomal sorting endosome microfilaments...
Articles
Biochem Soc Trans (2019) 47 (1): 37–45.
Published: 15 January 2019
...Han Han; Christopher P. Hill The progression of ESCRT (Endosomal Sorting Complexes Required for Transport) pathways, which mediate numerous cellular membrane fission events, is driven by the enzyme Vps4. Understanding of Vps4 mechanism is, therefore, of fundamental importance in its own right...
Articles
Biochem Soc Trans (2018) 46 (5): 1037–1046.
Published: 06 September 2018
... face of the endosome and generates vesicles that bud into the endosome lumen, but somehow escapes encapsulation itself. This machinery is termed the ESCRT (endosomal sorting complexes required for transport) pathway, a series of multi-protein complexes and accessory factors first identified in yeast...
Articles
Biochem Soc Trans (2017) 45 (3): 771–779.
Published: 15 June 2017
... cell migration endosomal sorting protein kinase B Rab5 trafficking Signaling endosomes are believed to function as platforms for integrating distinct communication pathways within cells [ 1 ]. Endosome-associated adaptor proteins are critical in mediating this cross-talk between signaling...
Articles
Biochem Soc Trans (2016) 44 (3): 891–897.
Published: 09 June 2016
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . endosomal sorting lysosomes receptors trafficking vacuole The plant vacuole was first discovered in 1676 by a Dutch scientist Antonie van Leeuwenhoek. Considered as the ‘father of microbiology...
Articles
Biochem Soc Trans (2015) 43 (1): 33–47.
Published: 26 January 2015
... the central importance of retromer to endosomal sorting, knocking out components of the mammalian retromer in model organisms is generally lethal. Disruption of VPS26A in mice results in embryonic arrest and lethality at day 9.5 [ 38 ] and knockout of VPS35 is lethal [ 39 ]. In contrast, VPS26B knockout mice...
Articles
Biochem Soc Trans (2011) 39 (5): 1179–1184.
Published: 21 September 2011
... Journal compilation © 2011 Biochemical Society 2011 early endosome endosomal sorting motor protein Rab protein sorting nexin (SNX) Eukaryotic cells are compartmentalized into distinct organelles that are composed of specific cohorts of proteins and lipids. Precise transport mechanisms...
Articles
Biochem Soc Trans (2010) 38 (6): 1397–1412.
Published: 24 November 2010
...Jeremy Carlton The ESCRT (endosomal sorting complex required for transport) machinery is a group of multisubunit protein complexes conserved across phyla that are involved in a range of diverse cellular processes. ESCRT proteins regulate the biogenesis of MVBs (multivesicular bodies...