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Keywords: endoplasmic reticulum stress
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Biochem Soc Trans (2017) 45 (5): 1067–1076.
Published: 22 September 2017
... of the contribution of both oxidative stress and endoplasmic reticulum stress in the development of neonatal brain injury and identify current preclinical therapeutic strategies. Correspondence: Claire Thornton ( claire.thornton@kcl.ac.uk ) Oxidative stress occurs when the generation of ROS and reactive...
Biochem Soc Trans (2008) 36 (3): 321–327.
Published: 21 May 2008
... to the attraction and activation of immune cells, leading to a ‘dialogue’ between the target β-cells and the invading immune cells [ 3 , 15 ]. There is, in parallel, an increased expression of MHC-related genes, which, coupled to cytokine-induced ER (endoplasmic reticulum) stress [ 16 , 17 ], may modify antigen...
Biochem Soc Trans (2007) 35 (5): 1205–1207.
Published: 25 October 2007
...T.P. Herbert To ensure cellular survival to ER (endoplasmic reticulum) stress, PERK [PKR (double-stranded-RNA-dependent protein kinase)-like ER kinase], an ER transmembrane kinase, is activated as part of the unfolded protein response. PERK is highly expressed in pancreatic β-cells and is essential...