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Keywords: endolysosomal system
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Biochem Soc Trans (2010) 38 (6): 1424–1431.
Published: 24 November 2010
... of intracellular Ca 2+ -release channels termed TPCs (two-pore channels) are components of the NAADP receptor. TPCs appear to be exclusively localized to the endolysosomal system. These findings confirm previous pharmacological and biochemical studies suggesting that NAADP targets acidic Ca 2+ stores rather than...