... disease amyloidosis C-reactive protein (CRP) drug target transthyretin (TTR) The ideal drug development project involves the elucidation of pathological biochemical or cellular processes in order to identify and target influential molecules; although this ideal can rarely be followed. Rather...

... million people worldwide each year. Thus an understanding of drug-resistance mechanisms, the immunobiology of cell wall components to elucidate host–pathogen interactions and the discovery of new drug targets are now required for the treatment of TB. Above the plasma membrane is a classical chemotype IV...

... worldwide each year. Thus an understanding of drug-resistance mechanisms, the immunobiology of cell wall components to elucidate host–pathogen interactions and the discovery of new drug targets are now required for the treatment of TB. Above the plasma membrane is a classical chemotype IV PG (peptidoglycan...

... Lo.Persson@med.lu.se 18 10 2006 © 2007 The Biochemical Society 2007 decarboxylase drug target ornithine decarboxylase (ODC) polyamine protozoan parasite S-adenosylmethionine Infectious diseases caused by protozoan parasites represent a major public health problem around...

... and MS. Because Mycobacterium tuberculosis DAPA AT is a potential drug target, this enzyme was cloned, overexpressed and purified to homogeneity for biochemical characterization. 1 Correspondence may be addressed to either of the authors (email mann@ccr.jussieu.fr or ploux@ccr.jussieu.fr...

...) pathway of isoprenoid formation. 1 To whom correspondence should be addressed (e-mail hartmut.lichtenthaler@bio-geo.uni-karlsruhe.de ) 26 6 2000 © 2000 Biochemical Society 2000 antibiotic drug target herbicide isoprene DOXP, deoxyxylulose 5-phosphate DXR, DOXP...