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Keywords: drug repurposing
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Articles

α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19

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Coronavirus
Spencer J. Williams, Ethan D. Goddard-Borger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1287–1295.
DOI: https://doi.org/10.1042/BST20200505
Published: 08 June 2020
... License 4.0 (CC BY) . Open access for this article was enabled by the participation of Walter and Eliza Hall Institute in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with CAUL. antiviral COVID-19 drug repurposing...
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Articles

Towards the routine use of in silico screenings for drug discovery using metabolic modelling

Tamara Bintener, Maria Pires Pacheco, Thomas Sauter
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 955–969.
DOI: https://doi.org/10.1042/BST20190867
Published: 05 May 2020
... in drug discovery. cancer drug repurposing drug target discovery metabolic modelling personalized medicine systems biology Since Otto Warburg, it is known that some cancer cells have an altered metabolism such as preferring the production of ATP from aerobic glycolysis over...
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Includes: Supplementary data