... the Plasmodium spp., are descendants of photosynthetic algae, and therefore they possess an essential plastid organelle, named the apicoplast. Since humans and animals have no plastids, the apicoplast is an attractive target for drug development. Indeed, after its discovery, the apicoplast was found to host...

... inositol phosphate cell-signalling drug pharmacology structure The inositol pyrophosphates (PP-IPs; Figure 1 ) comprise a unique class of cell-signalling molecules characterized by their functionally-significant and highly ‘energetic’ diphosphate groups [ 1 , 2 ]. As many as seven (‘InsP 7...