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Keywords: docking site
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Biochem Soc Trans (2006) 34 (5): 837–841.
Published: 25 October 2006
... several mechanisms that can promote specificity in MAPK signalling, including tethering interactions between MAPKs and their substrates and regulators mediated by docking sites, feedback loops and cross-pathway regulatory circuits, and the selective activation of scaffold proteins. Genetics studies...
Biochem Soc Trans (2006) 34 (5): 975–978.
Published: 25 October 2006
... that both proteins exhibit a common feature: a series of permanent or fluctuating, mostly hydrophobic, cavities of the protein matrix are providing transient docking sites as well as migration, escape and possibly entry pathways for the ligand. Remarkably, these systems of cavities connect the distal...