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Keywords: discontinuous replication
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Biochem Soc Trans (2014) 42 (1): 25–34.
Published: 23 January 2014
... is replicated in vivo is less clear. In fact, there have been many observations of discontinuous replication in the absence of exogenous DNA-damaging agents. It has also been proposed that replication is discontinuous on the leading strand at least in part because of DNA lesion bypass. Several recent studies...