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Keywords: disaggregase
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Biochem Soc Trans (2022) 50 (6): 1725–1736.
Published: 01 December 2022
... Limited on behalf of the Biochemical Society 2022 ATPase chaperone Clp disaggregase Hsp100 unfoldase Hsp100 unfoldases rescue proteins from an aggregated state or drive the degradation of misfolded polypeptides marked for proteolysis. Because Hsp100 unfoldases do not possess an intrinsic...
Biochem Soc Trans (2008) 36 (1): 120–125.
Published: 22 January 2008
... translates into specific mechanisms, reflecting adaptations to their respective functions. The ClpB-specific M-domain (middle domain) represents such an extra feature that verifies ClpB as the central disaggregase in vivo . M-domains act as regulatory devices to control both ClpB ATPase activity...