... and injury-induced conditions make TSPO an interesting, druggable target of mitochondrial metabolism. 1 email Philipp.Gut@rd.nestle.com . 20 1 2015 © 2015 Authors; published by Portland Press Limited 2015 diabetes mellitus metabolic disease mitochondria mitochondrial drugs PK...

... bacterium is the prelude to recurrent and persistent urinary tract infections in humans. Patients suffering from diabetes mellitus are more prone to contract urinary tract infections. In a study of women, despite longer treatments with a more potent antibiotic, these patients also have more often...

.... In addition, the action of VEGF makes the endothelium anti-apoptotic. In turn, the inhibition of VEGF action is associated with endothelial dysfunction. Likewise, endothelial dysfunction can be found in the presence of several cardiovascular risk factors, including diabetes mellitus, hypercholesterolaemia...

... 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 apoptosis diabetes mellitus lipoprotein lipotoxicity non-esterified fatty acid pancreatic β-cell In parallel with the increase in life expectancy of the last two centuries, lifestyles have changed...

...Decio L. Eizirik; Fabrice Moore; Daisy Flamez; Fernanda Ortis Accumulating evidence indicates that β-cells die by apoptosis in T1DM (Type 1 diabetes mellitus). Apoptosis is an active gene-directed process, and recent observations suggest that β-cell apoptosis depends on the parallel...

... for understanding how secretory functions can adapt to normal physiological conditions and shed light on the mechanisms involved in the development of important human diseases such as diabetes mellitus characterized by defective release of bioactive compounds. 1 To whom correspondence should be addressed...

...K. Kaňková Diabetes mellitus is the most common metabolic disease, and has late complications that are due to chronic hyperglycaemia. Altered carbohydrate and lipid metabolism together with impaired detoxification of carbonyl substrates and impaired trapping of oxygen radicals are responsible...