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Keywords: deubiquitylase
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Biochem Soc Trans (2017) 45 (5): 1137–1148.
Published: 22 September 2017
... ligases as well as hundreds of deubiquitylases, which reverse ubiquitin attachment. Moreover, there are hundreds of proteins with ubiquitin-binding domains that bind one of the eight possible polyubiquitin chains. Dysfunction of the ubiquitin system is associated with many diseases such as cancer...