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Keywords: desensitization
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Articles
Biochem Soc Trans (2005) 33 (6): 1333–1336.
Published: 26 October 2005
... of the regulation of β 2 -AR signalling by showing that β-arrestin-recruited PDE4 provides the means of desensitizing the agonist-dependent coupling of β 2 -AR with G i and its consequential activation of ERK. © 2005 The Biochemical Society 2005 A-kinase anchoring protein (AKAP) β 2 -adrenoceptor β...
Articles
Biochem Soc Trans (2004) 32 (6): 1025–1028.
Published: 26 October 2004
... assay, we also demonstrated that the interaction with NMDAR abolishes agonist-mediated D 1 R sequestration, indicating that oligomerization with NMDAR could represent a novel regulatory mechanism modulating D 1 R cellular trafficking and desensitization. 1 To whom correspondence should...
Articles
Biochem Soc Trans (2001) 29 (6): 641–654.
Published: 01 November 2001
.... 1 e-mail Therese.Kinsella@UCD.ie © 2001 Biochemical Society 2001 desensitization prostanoids TP receptor TXA 2 [Ca 2+ ], intracellular free Ca 2+ concentration COX, cyclo-oxygenase C-tail domain, C-terminal cytoplasmic domain ERK, extracellular-signal-regulated protein...