... Journal compilation © 2007 Biochemical Society 2007 NF-κB nuclear factor κB ABIN A20-binding inhibitor of NF-κB CYLD cylindromatosis DUB de-ubiquitinating enzyme IκB inhibitory κB IKK IκB kinase IL-1 interleukin-1 IL-1R IL-1 receptor IRAK1 IL-1R...

...-dependent kinase 4 DUB de-ubiquitinating enzyme Mdm2 murine double minute 2 UPS ubiquitin–proteasome system References 1 Welchman R.L. Gordon C. Mayer R.J. Nat. Rev. Mol. Cell Biol. 2005 6 599 609 2 Peng J. Schwartz D. Eliss J.E. Thoreen...

... the Ubiquitin, Proteasomes and Human Diseases mini-symposium, which is dedicated to the memory of Cecile Pickart. BRCA1 breast-cancer susceptibility gene 1 DUB de-ubiquitinating enzyme HA haemagglutinin HEK-293 cells human embryonic kidney cells I-Smad inhibitory Smad JAMM...

..., as most of the de-ubiquitinating enzymes have as yet no identified substrate, little is known about their potential role in the regulation of intracellular signalling. Here, we examine what is known about de-ubiquitinating enzymes and signalling, with particular emphasis on their role in the regulation...