... ] database searching, where other homologues were absent or separated by tens of orders of magnitude in E value. Similarly, many yeast proteins lacked any evident homologue in the trypanosomatid databases, even after more sensitive profile-based searches [ 10 ]. Between these situations, in only two cases...

... the identification of peptide tandem MS data, especially for peptides that currently give low or insignificant scores with current search algorithms. collision-induced dissociation database searching statistical analysis tandem mass spectra Abbreviations used: MS/MS, tandem MS; Xcorr, cross...