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Keywords: cytotoxicity
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Biochem Soc Trans (2020) 48 (2): 719–731.
Published: 08 April 2020
... different venoms demonstrate considerable cytotoxic effects on cancer cells via induction of apoptosis, cell cycle arrest and suppression of proliferation. These enzymes produce more pronounced cytotoxic effects in cancer cells than normal cells, thus they can be potential sources as chemotherapeutic agents...
Biochem Soc Trans (2007) 35 (2): 364–368.
Published: 20 March 2007
... patients to developing colorectal cancer by triggering the carcinogenic process at a much earlier age, as the mutation required to mutate APC normally takes many years to accumulate. chemoprevention colorectal cancer cytotoxicity non-steroidal anti-inflammatory drug (NSAID) polyamine...
Biochem Soc Trans (2007) 35 (2): 183–185.
Published: 20 March 2007
...A. Saudemont; K. Okkenhaug; F. Colucci NK cell (natural killer cells) are lymphocytes of innate immunity that kill tumour cells and respond to infections, without prior stimulation. A balance of activating and inhibitory signals regulates NK cell cytotoxicity, but the molecular mechanisms...
Biochem Soc Trans (2003) 31 (6): 1390–1393.
Published: 01 December 2003
...N. Shangari; W.R. Bruce; R. Poon; P.J. O'Brien Glyoxals are reactive α-oxoaldehydes that are formed endogenously from sugars, the levels of which are increased in various pathological conditions associated with hyperglycaemia and thiamine deficiency. However, the molecular cytotoxic mechanisms...
Biochem Soc Trans (2003) 31 (2): 407–410.
Published: 01 April 2003
... proliferation and viability. The assays performed suggested that apoptosis was not the principal cell death mechanism involved in oxa-polyamine cytotoxicity. In contrast, HL-60 cell death induced by the bisnaphthalimido series was characterized by early exposure of phosphatidylserine exclusive from membrane...
Biochem Soc Trans (2002) 30 (4): 401–405.
Published: 01 August 2002
... 2002 Biochemical Society 2002 ADP ribosylation coenzyme-binding site cytotoxicity ExoS, exoenzyme S GST, glutathione S-transferase NADE, p75NTR-associated cell-death executor 1 e-mail Bengt.Hallberg@cmb.umu.se 14-3-3 Proteins in Cell Regulation 13 14 15 16 17 18 19 20 21 22...
Biochem Soc Trans (2001) 29 (2): 341–345.
Published: 01 May 2001
... indicated that cancer cells may become enriched in CLA during growth in culture. This may make intracellular lipids more susceptible to ordinary levels of oxidative stress, to the point of producing a cytotoxic effect. Biochemical and Biomedical Aspects of Oxidative Modification 13 14 15 16 17 18 19 20...