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Keywords: cytosolic proteins
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Biochem Soc Trans (2021) 49 (1): 365–377.
Published: 26 February 2021
... and defective proteins from the cell. The ubiquitin-proteasome system is a key pathway for the molecular control of misfolded cytosolic proteins, co-opting a cascade of ubiquitin ligases to direct terminally damaged proteins to the proteasome via modification with chains of the small protein, ubiquitin. Despite...