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Articles

SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics

Irfan Saadi, Jeremy P. Goering, Brittany M. Hufft-Martinez, Pamela V. Tran

Biochem Soc Trans (2023) 51 (3): 949–958.

https://doi.org/10.1042/BST20220461

Published: 22 June 2023

... dynamics. Correspondence: Irfan Saadi ( isaadi@kumc.edu ) 1 3 2023 12 6 2023 13 6 2023 © 2023 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2023 cytoskeleton embryogenesis microfilaments microtubule model organisms molecular...

View article titled, SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics

Articles

Dynamics of phagocytosis mediated by phosphatidylserine

Daan Vorselen

Biochem Soc Trans (2022) 50 (5): 1281–1291.

https://doi.org/10.1042/BST20211254

Published: 25 October 2022

... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cytoskeleton efferocytosis immune receptors mechanobiology phagocytosis phosphatidylserine In a classical paper...

View article titled, Dynamics of phagocytosis mediated by phosphatidylserine

Articles

Studying actin-induced cell shape changes using Giant Unilamellar Vesicles and reconstituted actin networks

Rogério Lopes dos Santos, Clément Campillo

Biochem Soc Trans (2022) 50 (5): 1527–1539.

https://doi.org/10.1042/BST20220900

Published: 16 September 2022

...Rogério Lopes dos Santos; Clément Campillo Cell shape changes that are fuelled by the dynamics of the actomyosin cytoskeleton control cellular processes such as motility and division. However, the mechanisms of interplay between cell membranes and actomyosin are complicated to decipher...

View article titled, Studying actin-induced cell shape changes using Giant Unilamellar Vesicles and reconstituted actin networks

Articles

Effects of neuronal drebrin on actin dynamics

Elena E. Grintsevich

Biochem Soc Trans (2021) 49 (2): 685–692.

https://doi.org/10.1042/BST20200577

Published: 19 March 2021

...Elena E. Grintsevich Drebrin is a key regulator of actin cytoskeleton in neuronal cells which is critical for synaptic plasticity, neuritogenesis, and neuronal migration. It is also known to orchestrate a cross-talk between actin and microtubules. Decreased level of drebrin is a hallmark...

View article titled, Effects of neuronal drebrin on actin dynamics

Articles

The structure and function of protein kinase C-related kinases (PRKs)

Georgios Sophocleous, Darerca Owen, Helen R. Mott

Biochem Soc Trans (2021) 49 (1): 217–235.

https://doi.org/10.1042/BST20200466

Published: 01 February 2021

... the Creative Commons Attribution License 4.0 (CC BY) . Open access for this article was enabled by the participation of University of Cambridge in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. cytoskeleton...

View article titled, The structure and function of protein kinase C-related kinases (PRKs)

Articles

Class IA PI3K regulatory subunits: p110-independent roles and structures

Millie Fox, Helen R. Mott, Darerca Owen

Biochem Soc Trans (2020) 48 (4): 1397–1417.

https://doi.org/10.1042/BST20190845

Published: 17 July 2020

... for this article was enabled by the participation of University of Cambridge in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. cytoskeleton nuclear functions p85 phosphoinositide 3-kinase receptor trafficking...

View article titled, Class IA PI3K regulatory subunits: p110-independent roles and structures

Articles

The evolution of spherical cell shape; progress and perspective

Paul Richard Jesena Yulo, Heather Lyn Hendrickson

Biochem Soc Trans (2019) 47 (6): 1621–1634.

https://doi.org/10.1042/BST20180634

Published: 12 December 2019

... for cell shape are therefore the elements of the bacterial cytoskeleton, principally FtsZ, MreB, and the penicillin-binding proteins. MreB is particularly relevant in the transition between rod-like and spherical cell shape as it is often (but not always) lost early in the process. Here we will highlight...

View article titled, The evolution of spherical cell shape; progress and perspective

Includes: Supplementary data

Articles

The role of LRRK2 in cell signalling

Kirsten Harvey, Tiago F. Outeiro

Biochem Soc Trans (2019) 47 (1): 197–207.

https://doi.org/10.1042/BST20180464

Published: 21 December 2018

... contributes to novel diagnostic and therapeutic concepts in PD. Correspondence: Kirsten Harvey ( kirsten.harvey@ucl.ac.uk ) 15 10 2018 13 11 2018 19 11 2018 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 cytoskeleton...

View article titled, The role of LRRK2 in cell signalling

Articles

Parts list for a microtubule depolymerising kinesin

Claire T. Friel, Julie P. Welburn

Biochem Soc Trans (2018) 46 (6): 1665–1672.

https://doi.org/10.1042/BST20180350

Published: 22 November 2018

...Claire T. Friel; Julie P. Welburn The Kinesin superfamily is a large group of molecular motors that use the turnover of ATP to regulate their interaction with the microtubule cytoskeleton. The coupled relationship between nucleotide turnover and microtubule binding is harnessed in various ways...

View article titled, Parts list for a microtubule depolymerising kinesin

Articles

The role of LRRK2 in cytoskeletal dynamics

Laura Civiero, Susanna Cogo, Alice Biosa, Elisa Greggio

Biochem Soc Trans (2018) 46 (6): 1653–1663.

https://doi.org/10.1042/BST20180469

Published: 22 November 2018

... on a functional cytoskeleton for many homeostatic processes such as local and long-distance vesicle transport, synaptic plasticity, and dendrites/axons growth and remodeling. Here, we will review the available data linking LRRK2 and the cytoskeleton, and discuss how this may be functionally relevant for the well...

View article titled, The role of LRRK2 in cytoskeletal dynamics

Articles

New nuclear and perinuclear functions of formins

Tadamoto Isogai, Metello Innocenti

Biochem Soc Trans (2016) 44 (6): 1701–1708.

https://doi.org/10.1042/BST20160187

Published: 02 December 2016

... and microtubule dynamics. Not surprisingly, formins are best known as key regulators of the cytoskeleton in a variety of morphogenetic processes. However, mounting evidence implicates several formins in the assembly and organization of actin within and around the nucleus. In addition, actin-independent roles...

View article titled, New nuclear and perinuclear functions of formins

Articles

The Borg family of Cdc42 effector proteins Cdc42EP1–5

Aaron J. Farrugia, Fernando Calvo

Biochem Soc Trans (2016) 44 (6): 1709–1716.

https://doi.org/10.1042/BST20160219

Published: 02 December 2016

...@icr.ac.uk ) 30 7 2016 15 9 2016 19 9 2016 © 2016 The Author(s) 2016 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Borg Cdc42 cytoskeleton...

View article titled, The Borg family of Cdc42 effector proteins Cdc42EP1–5

Articles

Diaphanous-related formin 1 as a target for tumor therapy

Yuan-Na Lin, Sabine Windhorst

Biochem Soc Trans (2016) 44 (5): 1289–1293.

https://doi.org/10.1042/BST20160120

Published: 19 October 2016

... to integrin-β1 alters the F-actin structure, resulting in consolidation of adhesion. Thus, both cell spreading and formation of FAs depend on MTs. cytoskeleton tumor cell adhesion vesicle trafficking Metastasis is the leading cause of death in cancer patients [ 1 , 2 ]. The first step...

View article titled, Diaphanous-related formin 1 as a target for tumor therapy

Articles

How myosin organization of the actin cytoskeleton contributes to the cancer phenotype

Michelle Peckham

Biochem Soc Trans (2016) 44 (4): 1026–1034.

https://doi.org/10.1042/BST20160034

Published: 15 August 2016

..., at least one class 2 gene and classes 5, 6, 9, 10, 18 and 19. Although the different myosin isoforms all have specific and non-overlapping roles in the cell, in combination they all contribute to the organization of the actin cytoskeleton, and the shape and phenotype of the cell. Over (or under) expression...

View article titled, How myosin organization of the actin <span class="search-highlight">cytoskeleton</span> contributes to the cancer phenotype

Articles

Pushing with actin: from cells to pathogens

J. Victor Small

Biochem Soc Trans (2015) 43 (1): 84–91.

https://doi.org/10.1042/BST20140184

Published: 26 January 2015

... ET, we have shown that baculovirus generates at its rear a fishbone-like array of subsets of branched actin filaments, with an average of only four filaments engaged in pushing at any one time. In both of these studies, the application of ET of negatively stained cytoskeletons for higher filament...

View article titled, Pushing with actin: from cells to pathogens

Articles

RNA granules and cytoskeletal links

Dipen Rajgor, Catherine M. Shanahan

Biochem Soc Trans (2014) 42 (4): 1206–1210.

https://doi.org/10.1042/BST20140067

Published: 11 August 2014

.... SGs and P-bodies are related to NGs (neuronal granules), which are essential in the localization and control of mRNAs in neurons. Importantly, RNA granules are linked to the cytoskeleton, which plays an important role in mediating many of their dynamic properties. In the present review, we discuss how...

View article titled, RNA granules and cytoskeletal links

Articles

Interactions between Epac1 and ezrin in the control of endothelial barrier function

Euan Parnell, Stephen J. Yarwood

Biochem Soc Trans (2014) 42 (2): 274–278.

https://doi.org/10.1042/BST20130271

Published: 20 March 2014

... protein directly activated by cAMP). The present review outlines the role of Epac1 signalling within the endothelium and, in particular, the role of Epac1 in cytoskeletal dynamics and the control of cell morphology. The actin/cytoskeleton linker ezrin will be described in terms of the growing body...

View article titled, Interactions between Epac1 and ezrin in the control of endothelial barrier function

Articles

Self-incompatibility in Papaver : advances in integrating the signalling network

Deborah J. Eaves, Carlos Flores-Ortiz, Tamanna Haque, Zongcheng Lin, Nianjun Teng, Vernonica E. Franklin-Tong

Biochem Soc Trans (2014) 42 (2): 370–376.

https://doi.org/10.1042/BST20130248

Published: 20 March 2014

... transmembrane protein. Interaction of matching pollen and pistil S -determinants results in self-recognition, initiating a Ca 2+ -dependent signalling network in incompatible pollen. This triggers several downstream events, including alterations to the cytoskeleton, phosphorylation of sPPases (soluble inorganic...

View article titled, Self-incompatibility in Papaver : advances in integrating the signalling network

Articles

Cdc42 regulates polarized growth and cell integrity in fission yeast

Sergio A. Rincón, Miguel Estravís, Pilar Pérez

Biochem Soc Trans (2014) 42 (1): 201–205.

https://doi.org/10.1042/BST20130155

Published: 23 January 2014

...Sergio A. Rincón; Miguel Estravís; Pilar Pérez Polarized cell growth requires a well-orchestrated number of events, namely selection of growth site, organization of cytoskeleton elements and delivery of new material to the growth region. The small Rho GTPase Cdc42 has emerged as a major organizer...

View article titled, Cdc42 regulates polarized growth and cell integrity in fission yeast

Articles

Formin-based control of the actin cytoskeleton during cytokinesis

K. Adam Bohnert, Alaina H. Willet, David R. Kovar, Kathleen L. Gould

Biochem Soc Trans (2013) 41 (6): 1750–1754.

https://doi.org/10.1042/BST20130208

Published: 20 November 2013

... 2013 Biochemical Society 2013 actin cytokinesis cytoskeleton formin How are the actin assembly properties of the formin FH1–FH2 core regulated? A common mode of formin regulation involves two additional formin domains, the N-terminal DID (diaphanous inhibitory domain) and the C...

View article titled, Formin-based control of the actin <span class="search-highlight">cytoskeleton</span> during cytokinesis

Articles

Microtubules: greater than the sum of the parts

Jonathan L.D. Lawson, Rafael E. Carazo Salas

Biochem Soc Trans (2013) 41 (6): 1736–1744.

https://doi.org/10.1042/BST20130239

Published: 20 November 2013

...Jonathan L.D. Lawson; Rafael E. Carazo Salas The post-genomic era has produced a variety of new investigation technologies, techniques and approaches that may offer exciting insights into many long-standing questions of scientific research. The microtubule cytoskeleton is a highly conserved system...

View article titled, Microtubules: greater than the sum of the parts

Articles

LRRK2 and vesicle trafficking

Giovanna Sanna, Maria Grazia Del Giudice, Claudia Crosio, Ciro Iaccarino

Biochem Soc Trans (2012) 40 (5): 1117–1122.

https://doi.org/10.1042/BST20120117

Published: 19 September 2012

... role of LRRK2 in the regulation of membrane trafficking from vesicle generation to the movement along cytoskeleton and finally to vesicle fusion with cell membrane. 1 To whom correspondence should be addressed (email ciaccarino@uniss.it ). 2 5 2012 © The Authors Journal...

View article titled, LRRK2 and vesicle trafficking

Articles

Insights into LRRK2 function and dysfunction from transgenic and knockout rodent models

Maximilian Sloan, Javier Alegre-Abarrategui, Richard Wade-Martins

Biochem Soc Trans (2012) 40 (5): 1080–1085.

https://doi.org/10.1042/BST20120151

Published: 19 September 2012

... correspondence should be addressed (email javier.alegre@dpag.ox.ac.uk ). 25 6 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 autophagy cytoskeleton dopamine leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease tau Mutations in the LRRK2 (leucine-rich...

View article titled, Insights into LRRK2 function and dysfunction from transgenic and knockout rodent models

Articles

Uses of the in vitro endothelial–fibroblast organotypic co-culture assay in angiogenesis research

Clare Hetheridge, Georgia Mavria, Harry Mellor

Biochem Soc Trans (2011) 39 (6): 1597–1600.

https://doi.org/10.1042/BST20110738

Published: 21 November 2011

... The Authors Journal compilation © 2011 Biochemical Society 2011 angiogenesis cell co-culture cytoskeleton endothelial cell fibroblast Matrigel assay Angiogenesis is the process by which new blood vessels form from pre-existing vasculature. Angiogenesis is most active during development...

View article titled, Uses of the in vitro endothelial–fibroblast organotypic co-culture assay in angiogenesis research

Articles

Organelle Biogenesis and Positioning in Plants

David E. Evans, Chris Hawes

Biochem Soc Trans (2010) 38 (3): 729–732.

https://doi.org/10.1042/BST0380729

Published: 24 May 2010

.... Probing cytoplasmic organisation and the actin cytoskeleton of plant cells with optical tweezers Biochem. Soc. Trans. 2010 38 823 828 38 van der Honing H.S. de Ruijter N.C.A. Emons A.M.C. Ketelaar T. Actin and mysoin regulate cytoplasm stiffness in plant cells; a study using...

View article titled, Organelle Biogenesis and Positioning in Plants

Articles

Mitochondrial fusion, division and positioning in plants

David C. Logan

Biochem Soc Trans (2010) 38 (3): 789–795.

https://doi.org/10.1042/BST0380789

Published: 24 May 2010

.... Mitochondria are highly motile and movement on the cytoskeleton ensures that the physically discrete organelles come into contact with one another, which allows transient fusion, followed by division of the mitochondrial membranes. This article serves to review our current knowledge of mitochondrial fusion...

View article titled, Mitochondrial fusion, division and positioning in plants

Articles

Networking in the endoplasmic reticulum

Lawrence R. Griffing

Biochem Soc Trans (2010) 38 (3): 747–753.

https://doi.org/10.1042/BST0380747

Published: 24 May 2010

...’. With latrunculin B treatment, we have investigated the involvement of actin in the elongation and persistency of the tubules. We also show how the cytoskeleton is involved in directional diffusion within the membrane. This observation may lead to an answer to the question of what function this network structure...

View article titled, Networking in the endoplasmic reticulum

Articles

KASH-domain proteins and the cytoskeletal landscapes of the nuclear envelope

Maria Schneider, Angelika A. Noegel, Iakowos Karakesisoglou

Biochem Soc Trans (2008) 36 (6): 1368–1372.

https://doi.org/10.1042/BST0361368

Published: 19 November 2008

... (anchorage 1)/SYNE (synaptic nuclear envelope protein) homology]-domain family, which function primarily as exclusive outer nuclear membrane scaffolds that associate with the cytoskeleton, the centrosome and the motor protein apparatus. In the present paper, we propose a novel model, which may explain why...

View article titled, KASH-domain proteins and the cytoskeletal landscapes of the nuclear envelope

Articles

Regulation of cell–cell adhesion by the cadherin–catenin complex

W. James Nelson

Biochem Soc Trans (2008) 36 (2): 149–155.

https://doi.org/10.1042/BST0360149

Published: 20 March 2008

... in the organization of the actin cytoskeleton. Although cadherins were thought to bind directly to the actin cytoskeleton through cytoplasmic proteins, termed α- and β-catenin, recent studies with purified proteins indicate that the interaction is not direct, and instead an allosteric switch in α-catenin may mediate...

View article titled, Regulation of cell–cell adhesion by the cadherin–catenin complex

Articles

F-actin cytoskeletal organization in intervertebral disc health and disease

S. Li, V.C. Duance, E.J. Blain

Biochem Soc Trans (2007) 35 (4): 683–685.

https://doi.org/10.1042/BST0350683

Published: 20 July 2007

...S. Li; V.C. Duance; E.J. Blain The cytoskeleton, which in most cell types, including the intervertebral disc described here, comprises microfilaments, microtubules and intermediate filaments, plays important functions in many fundamental cellular events, including cell division, motility, protein...

View article titled, F-actin cytoskeletal organization in intervertebral disc health and disease

Articles

Plasmodesmata and intercellular transport of viral RNA

C. Hofmann, A. Sambade, M. Heinlein

Biochem Soc Trans (2007) 35 (1): 142–145.

https://doi.org/10.1042/BST0350142

Published: 22 January 2007

... manfred.heinlein@ibmp-ulp.u-strasbg.fr ). 17 8 2006 © 2007 The Biochemical Society 2007 cytoskeleton macromolecular transport movement protein plasmodesmata replicase tobacco mosaic virus Intercellular communication delivers crucial information for the position-dependent...

View article titled, Plasmodesmata and intercellular transport of viral RNA

Articles

Retrograde signalling at the synapse: a role for Wnt proteins

P.C. Salinas

Biochem Soc Trans (2005) 33 (6): 1295–1298.

https://doi.org/10.1042/BST0331295

Published: 26 October 2005

.... Parmentier M.L. Grau Y. J. Neurosci. 2004 24 6573 6577 22 Dillon C. Goda Y. Annu. Rev. Neurosci. 2005 28 25 55 22 6 2005 © 2005 The Biochemical Society 2005 cytoskeleton glycogen synthase kinase-3β (GSK-3β) microtubule synapse...

View article titled, Retrograde signalling at the synapse: a role for Wnt proteins

Articles

Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation

I. Näthke

Biochem Soc Trans (2005) 33 (4): 694–697.

https://doi.org/10.1042/BST0330694

Published: 01 August 2005

... the normal maintenance of this tissue: differentiation, migration, proliferation and apoptosis. Indeed, APC is involved in the regulation of β-catenin and it also is an important regulator of the cytoskeleton. Thus mutations in APC lead to the accumulation of β-catenin, which causes changes...

View article titled, Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation

Articles

Control of SCAR activity in Dictyostelium discoideum

S.L. Blagg, R.H. Insall

Biochem Soc Trans (2004) 32 (6): 1113–1114.

https://doi.org/10.1042/BST0321113

Published: 26 October 2004

... 2004 cytoskeleton Dictyostelium motility Nap1 PIR121 suppressor of cAMP receptor (SCAR) Research Colloquia: Research Colloquia at BioScience2004, held at SECC Glasgow, U.K., 18–22 July 2004. Edited by M. Bouvier (Montreal, Canada), G. Milligan (Glasgow, U.K.), V. O'Donnell (Cardiff...

View article titled, Control of SCAR activity in Dictyostelium discoideum

Articles

Interactions between G-protein-coupled receptors and periplakin: a selective means to regulate G-protein activation

G. Milligan, H. Murdoch, E. Kellett, J.H. White, G.-J. Feng

Biochem Soc Trans (2004) 32 (5): 878–880.

https://doi.org/10.1042/BST0320878

Published: 26 October 2004

.... 1 To whom correspondence should be addressed (email g.milligan@bio.gla.ac.uk ). 6 6 2004 © 2004 The Biochemical Society 2004 cytoskeleton G-protein G-protein-coupled receptor melanin concentrating hormone opioid plakin Although initially considered to exist...

View article titled, Interactions between G-protein-coupled receptors and periplakin: a selective means to regulate G-protein activation

Articles

Mechanisms of integration of cells and extracellular matrices by integrins

M.J. Humphries, M.A. Travis, K. Clark, A.P. Mould

Biochem Soc Trans (2004) 32 (5): 822–825.

https://doi.org/10.1042/BST0320822

Published: 26 October 2004

... the contractile cytoskeleton to the plasma membrane, but there is also evidence that integrin receptors modulate signalling events that are essential for cellular differentiation. A major challenge is now to integrate work at the atomic, molecular and cellular levels, and obtain holistic insights...

View article titled, Mechanisms of integration of cells and extracellular matrices by integrins

Articles

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

D.R. Critchley

Biochem Soc Trans (2004) 32 (5): 831–836.

https://doi.org/10.1042/BST0320831

Published: 26 October 2004

... protein kinase C VBS vinculin-binding site Vh vinculin head Vt vinculin tail cytoskeleton focal adhesions integrin talin vinculin The integrin family of cell adhesion molecules are coupled to the actin cytoskeleton [ 1 ] with the exception of integrin α6β4, which...

View article titled, Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

Articles

Lysophosphatidic acid: mitogen and motility factor

F.N. van Leeuwen, B.N.G. Giepmans, L.A. van Meeteren, W.H. Moolenaar

Biochem Soc Trans (2003) 31 (6): 1209–1212.

https://doi.org/10.1042/bst0311209

Published: 01 December 2003

... 2003 Biochemical Society 2003 cytoskeleton lysophosphatidic acid (LPA) motility phospholipase Rho GTPase Tiam1 Abbreviations used: LPA, lysophosphatidic acid; GPCR, G-protein-coupled receptor; PI 3-kinase, phosphoinositide 3-kinase; EGF, epidermal growth factor; PLD, phospholipase...

View article titled, Lysophosphatidic acid: mitogen and motility factor

Articles

Activated M-phase-promoting factor (MPF) is exported from the nucleus of starfish oocytes to increase the sensitivity of the Ins(1,4,5)P3 receptors

L. Santella, E. Ercolano, D. Lim, G.A. Nusco, F. Moccia

Biochem Soc Trans (2003) 31 (1): 79–82.

https://doi.org/10.1042/bst0310079

Published: 01 February 2003

... meeting held at University of Liverpool, Liverpool, 4–6 September 2002 6 September 2002 Copyright 2003 Biochemical Society 2003 cytoskeleton nucleus Abbreviations used: ADF; actin depolymerization factor; BAPTA, bis-( o -aminophenoxy)ethane- N,N,N´,N´ -tetra-acetic acid...

View article titled, Activated M-phase-promoting factor (MPF) is exported from the nucleus of starfish oocytes to increase the sensitivity of the Ins(1,4,5)P3 receptors

Articles

A-kinase-anchoring proteins and cytoskeletal signalling events

J.D. Scott

Biochem Soc Trans (2003) 31 (1): 87–89.

https://doi.org/10.1042/bst0310087

Published: 01 February 2003

...J.D. Scott Targeting of protein kinases and phosphatases to the cytoskeleton enhances the regulation of many signalling events. Cytoskeletal signalling complexes facilitate this process by optimizing the relay of messages from membrane receptors to specific sites on the actin cytoskeleton...

View article titled, A-kinase-anchoring proteins and cytoskeletal signalling events

Articles

Hepatocyte couplets

R. Coleman, M. G. Roma

Biochem Soc Trans (2000) 28 (2): 136–140.

https://doi.org/10.1042/bst0280136

Published: 01 February 2000

... -aminophenoxy)ethane- N,N ,N’,N’-tetra-acetic acid acetoxymethyl ester PKA, protein kinase A PKC, protein kinase C bile formation cholestasis cytoskeleton polarized cells tight junctions Biochemical Society Transactions (2000) Volume 28, part 2 Hepatocyte couplets R. Coleman*' and M. G. Romat...

View article titled, Hepatocyte couplets

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