...-13Rα2. 1 To whom correspondence should be addressed (email ala@soton.ac.uk ). 8 3 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 asthma cytokine receptor interleukin 4 (IL-4) interleukin 13 (IL-13) interleukin 13 receptor α-chain 1 (IL-13Rα1...

...Irma Lemmens; Sam Lievens; Jan Tavernier MAPPIT (mammalian protein–protein interaction trap) is a cytokine receptor-based two-hybrid method that operates in intact mammalian cells. A bait is fused C-terminally to a STAT (signal transducer and activator of transcription) recruitment-deficient...

... phosphorylation and activation of STAT proteins, and discuss possible mechanisms by which intracellular cAMP sensors could interact with these inhibitory processes to diminish cytokine receptor-mediated pro-inflammatory signalling. One potential strategy for limiting endothelial dysfunction is to enhance...