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Keywords: cytochrome P450 reductase
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Biochem Soc Trans (2006) 34 (6): 1186–1191.
Published: 25 October 2006
...A.V. Pandey All microsomal P450s require POR (cytochrome P450 reductase) for catalytic activity. Most of the clinically used drugs are metabolized by a small number of P450s and polymorphisms in the cytochrome P450s are known to cause changes in drug metabolism. We have recently found a number...
Biochem Soc Trans (2003) 31 (3): 497–501.
Published: 01 June 2003
...A. Gutierrez; A. Grunau; M. Paine; A.W. Munro; C.R. Wolf; G.C.K. Roberts; N.S. Scrutton Cytochrome P450 reductase (CPR) is a diflavin enzyme responsible for electron donation to mammalian cytochrome P450 enzymes in the endoplasmic reticulum. Dissection of the enzyme into functional domains...