...Mark Shepherd The CydDC complex of Escherichia coli is a heterodimeric ATP-binding cassette (ABC) transporter that exports cysteine and glutathione to the periplasm. These reductants are thought to modulate periplasmic redox poise, impacting upon the disulfide folding of periplasmic and secreted...

... of reduction of oxidative agents, as well as in the reactivity of the catalytically active residues, confer peculiar features on them. Ultimately, Gpx should be regarded as an efficient peroxides scavenger having a high-reactive selenocysteine (Sec) residue. Prx, by having a low p K a cysteine, is less...

...Christian Schöneich Cysteine thiyl radicals engage in reversible intramolecular hydrogen-transfer reactions with amino acid residues in peptides and proteins. These reactions can be experimentally demonstrated through covalent hydrogen–deuterium exchange when experiments are carried out in 2 H 2 O...

...Claus Jacob Research conducted during the last two decades has provided evidence for the existence of an extensive intracellular redox signalling, control and feedback network based on different cysteine-containing proteins and enzymes. Together, these proteins enable the living cell to sense...

... glimpses of how DHHC-substrate specificity might be achieved. 1 To whom correspondence should be addressed (email J.Greaves@ed.ac.uk ). 17 1 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 cysteine DHHC protein membrane topology palmitoylation S...