... systems, and can facilitate the study of these mediators. 1 To whom correspondence should be addressed (email a.nicolaou@bradford.ac.uk ). 27 5 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cyclo-oxygenase (COX) cytochrome P450 (CYP450) eicosanoid...

... Society 2009 angiogenesis arachidonic acid cyclo-oxygenase (COX) endothelial cell prostanoid protease-activated receptor (PAR) The initial step in the formation of prostanoids by endothelial cells is the stimulus-induced liberation of AA (arachidonic acid) from the sn -2 position...

... of colon carcinogenesis in subjects at risk for colon cancer. It is clinical trials that will ultimately determine the role of NO-NSAIDs in cancer prevention and perhaps treatment. cancer chemoprevention cyclo-oxygenase (COX) nitric oxide (NO) NO-aspirin NO-donating non-steroidal anti-inflammatory...

... 12 2006 © 2007 Biochemical Society 2007 chylomicron remnant-like particle cyclo-oxygenase (COX) endothelial cell haem oxygenase-1 (HO-1) mitogen-activated protein kinase (MAPK) prostanoid EC (endothelial cell) dysfunction is characterized by impairment of endothelial...

...S. Toomey; H. Roche; D. Fitzgerald; O. Belton Conjugated linoleic acid (CLA) refers to a group of positional and geometric isomers of linoleic acid that has been shown to suppress the development of atherosclerosis in a rabbit model. We investigated whether CLA acts as a cyclo-oxygenase (COX...