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Keywords: cybrid
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Biochem Soc Trans (2013) 41 (1): 118–123.
Published: 29 January 2013
... to increased platelet activation in diabetes, Avila et al. [ 6 ] recently showed that platelets from diabetic patients had decreased rates of oxygen consumption and hallmark signs of increased ROS generation. cybrid cytochrome c redox signalling platelet mitochondria The traditional view...
Biochem Soc Trans (2006) 34 (5): 824–827.
Published: 25 October 2006
... in mitochondrial function. Recently, we used clonal cytosolic hybrid cells (namely cybrids) harbouring mitochondria derived from MIDD patients. Compared with control mtDNA from the same patient, the A3243G mutation markedly modified metabolic pathways. Moreover, cybrid cells carrying patient-derived mutant mtDNA...