... Journal compilation © 2015 Biochemical Society 2015 conductance connexin fluorescent dye hemichannel activity phosphorylation protein kinase C Direct intercellular communication is maintained by gap junctional channels, which are composed of connexins [ 1 ]. Connexins are four...

... correspondence should be addressed (email beverley.orser@utoronto.ca ). 6 7 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 benzodiazepine brain conductance γ-aminobutyric acid subtype A receptor (GABA A R) hippocampal pyramidal neuron long-term potentiation (LTP...

... and channel blockers as well as showing marked differences in their single-channel conductances and deactivation kinetics. Here, we describe a series of experiments where we have generated and studied two chimaeric GluN2A/GluN2D subunits. The first chimaera, referred to as GluN2A(2D-M1M2M3), replaces...

... the magnitude (conductance) of ion flow into the cell. Thus the Cys-loop receptors are complex molecular motors, with moving parts, which can transduce extracellular signals across the plasma membrane. Once the full mechanical motions involved are understood, it may be possible to design sophisticated...