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Keywords: combination therapy
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Biochem Soc Trans (2020) 48 (3): 1101–1108.
Published: 07 May 2020
... of genomic aberration. Although adaptive responses results in drug resistance, it also induces therapeutic vulnerabilities that could be exploited with rational combination therapies. To fulfill this role, we established the combinatorial adaptive response therapy (CART) platform by performing reverse-phase...
Biochem Soc Trans (2014) 42 (6): 1608–1615.
Published: 17 November 2014
... angiogenesis inhibitors can only arise from two efforts. First, through the identification of better targets, preferably specifically expressed in the tumour vasculature. Secondly, through the development of combination therapies. The present review highlights the current efforts and challenges in trying...